A novel cancer vaccine is moving to Phase 1 human trials in the United States after promising results from animal studies showed encouraging efficacy and a robust safety profile. A new study describes the vaccine as producing complete responses in 90 percent of animals when combined with a second immunotherapy drug.
The best way to fight off cancer might be to strengthen the body’s immune system and help it identify and kill tumors. This field of study is known as immunotherapy, and while it’s showing promise it can be quite expensive. Now, researchers at the University of Wisconsin-Madison have developed artificial nanoparticles that should be cheaper and easier to produce.
The immune system is already our best defense against cancer, but sometimes it needs help. After all, cancer has a knack for deceiving it and hiding from immune cells, giving itself time to grow and spread. Now, researchers at QIMR Berghofer Medical Research Institute in Australia have identified one way it does so, and found a method to counter it in mouse tests.
The cure for cancer might have been inside us all along – our own immune system. The trick is to give it a boost to find and destroy those rogue cells, and that’s the focus of the field of immunotherapy. To that end, a new hydrogel has been developed that can be injected directly to the site of a tumor, where it stays to slowly release its payload of immunotherapy drugs for longer.