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A Brain Cancer Vaccine?

A new vaccine is designed to help train immune cells to target a mutation unique to brain tumors
A new vaccine is designed to help train immune cells to target a mutation unique to brain tumors

A new article published in the journal Nature is reporting promising results from a landmark Phase 1 human trial testing a novel vaccine designed to help a patient’s immune system better target brain tumors. The data suggests the experimental vaccine is safe and stimulates a significant immune response that slows tumor progression. A larger Phase 2 trial is currently being planned. read more

Ebola May Help Kill Cancer

The Ebola virus has emerged as an unlikely potential ally in the fight against deadly brain cancer
The Ebola virus has emerged as an unlikely potential ally in the fight against deadly brain cancer

Glioblastomas are highly aggressive brain tumors that are notoriously difficult to treat, with the cancer cells often slipping away from the main growth and into the brain, leading to high rates of recurrence down the track. In search of more effective therapies, scientists are investigating how the cell-destroying abilities of certain viruses can be leveraged to better remove the threat. A team at Yale University is now reporting an exciting breakthrough in this area, with components of the Ebola virus put to use in a promising new therapy that proved capable of killing glioblastomas in mice. read more

New Drug Delivery for Brain Cancer

An artist's rendition of MIT's new nanoparticles, which can carry two forms of drug to combat...
An artist’s rendition of MIT’s new nanoparticles, which can carry two forms of drug to combat brain cancer(Credit: Stephen Morton)

Glioblastoma is one of the most deadly forms of cancer. Affecting the brain, those unlucky enough to receive a diagnosis don’t have many treatment options – and usually a median life expectancy of just over a year. Now, researchers at MIT have developed nanoparticles that could provide hope, crossing the blood-brain barrier and delivering two types of drugs to fight tumors. read more