Positive early results from the first phase of human testing for a unique colorectal cancer vaccine are proving promising. A newly published study outlining the Phase I trial results suggests the vaccine is safe, and stimulates immune activation, paving the way for larger human trials.
Colorectal cancer is the second biggest cancer killer globally. It is not only tricky to diagnose early, but many current treatments are only marginally effective. Almost half of patients receiving surgical resections still don’t survive due to the cancer’s propensity for recurrence.
The new vaccine treatment is designed to stimulate a patient’s immune system to attack and destroy the cancer. Immunotherapy treatments traditionally work by training the immune system to recognize a foreign agent so it is primed to identify and kill those substances when they naturally appear in the body. Tumor cells are notoriously tricky to target in this regard as they often closely resemble normal healthy cells.