Say Goodbye to Fillings

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The drug promotes natural repair by stimulating the stem cells in the tooth pulp
The drug promotes natural repair by stimulating the stem cells in the tooth pulp(Credit:pressmaster/Depositphotos)


There’s not a whole lot to like about fillings, what with the prodding, scraping and jabbing and all. And that’s before the drill even comes out (followed by the bill at the end). Tending to our cavities might one day be a much more comfortable experience, with scientists discovering that a type of Alzheimer’s drug can actually stimulate stem cells within the tooth pulp to promote natural repair instead.

The drug in question is a small molecule called a glycogen synthase kinase (GSK-3) inhibitor.

GSK-3 is an enzyme that has been linked with a number of diseases including cancer, bipolar disorder and Alzheimer’s, so molecules currently under development that inhibit its activity could one day play an important part in treatment of such conditions.

Now, scientists at King’s College London have found that such inhibitors could have a role in maintaining pearly whites, too. Their research focuses on a signaling pathway called Wnt/β-cat, which is activated as an early response to tissue damage, and is thought to be critical for driving cellular-based repair in all tissues. By further promoting its activity in teeth, the team believes that they can enhance their self-repairing capabilities.

“The inhibitor activates a signaling pathway that stimulates stem cells in the tooth to make specialized cells that carry out the repair,” Paul Sharpe, lead author of the study, tells New Atlas.

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About the Common Constitutionalist

Brent, aka The Common Constitutionalist, is a Constitutional Conservative, and advocates for first principles, founders original intent and enemy of progressives. He is former Navy, Martial Arts expert. As well as publisher of the Common Constitutionalist blog, he also is a contributing writer for Political Outcast, Godfather Politics, Minute Men News (Liberty Alliance), Freedom Outpost, the Daily Caller, Vision To America and Free Republic. He also writes an exclusive weekly column for World Net Daily (WND).

One comment on “Say Goodbye to Fillings

  1. Pingback: Say Goodbye to Fillings – USSA News | The Tea Party's Front Page

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