Reprogramming Immune Cells to Kill Cancer

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Researchers have reprogrammed immune cells that were previously hijacked by cancer to wipe out the disease
Researchers have reprogrammed immune cells that were previously hijacked by cancer to wipe out the disease

One of cancer’s crafty tricks involves manipulating the host’s immune cells to protect the tumors instead of fighting them. But now, researchers at Massachusetts General Hospital (MGH) have turned the tables around again, transforming these cells back into cancer killers.

In a fair fight between the immune system and cancer, the immune system would win most of the time. But cancer doesn’t fight fair – it uses a range of underhanded tricks to gain the upper hand. To promote its own growth, cancer creates its own microenvironment around it to sap nutrients and weaken the immune response in the area.

One of the most devious ways it does this is by hijacking the function of immune cells called regulatory T cells (Tregs). Normally these cells play an important role in keeping the immune system from attacking the body’s own cells, which would lead to autoimmune diseases. But some types of cancer will selectively let Tregs into their microenvironment, where they then fight off other immune cells that come to kill the tumor.

About the Common Constitutionalist

Brent, aka The Common Constitutionalist, is a Constitutional Conservative, and advocates for first principles, founders original intent and enemy of progressives. He is former Navy, Martial Arts expert. As well as publisher of the Common Constitutionalist blog, he also is a contributing writer for Political Outcast, Godfather Politics, Minute Men News (Liberty Alliance), Freedom Outpost, the Daily Caller, Vision To America and Free Republic. He also writes an exclusive weekly column for World Net Daily (WND).