New Drug Shreds Cancer Proteins

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Researchers have developed a drug that can destroy proteins associated with cancer growth
Researchers have developed a drug that can destroy proteins associated with cancer growth

Researchers in Germany have developed a new drug that can act like a “shredder” for proteins implicated in causing cancer. In tests on lab-grown cancer cells, the drug worked to kill the tumors, suggesting a new pathway to a treatment for the disease.

In higher-than-usual amounts, some proteins have been linked to an increased risk of cancer, and Aurora-A kinase (or just Aurora) has long been known to be among them. This protein is overexpressed in some breast and prostate cancers, leukemias and neuroblastomas, among others.

Inhibiting these “tumorigenic” proteins is one avenue of cancer treatment that scientists are exploring. But usually drugs just shut down the proteins without destroying them, which helps fight the tumor but doesn’t stop the proteins’ functions entirely. Unfortunately, these kinds of drugs haven’t yet proven too effective in tests.

“Aurora-A kinase is present in much higher concentrations in many cancer tissues than in healthy tissue and it also plays a key role in prostate cancer,” says Stefan Knapp, an author of the study. “Blocking the activity of Aurora-A kinase alone seems not a promising approach as none of the many clinically tested drug candidates has achieved clinical approval.”

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Brent, aka The Common Constitutionalist, is a Constitutional Conservative, and advocates for first principles, founders original intent and enemy of progressives. He is former Navy, Martial Arts expert. As well as publisher of the Common Constitutionalist blog, he also is a contributing writer for Political Outcast, Godfather Politics, Minute Men News (Liberty Alliance), Freedom Outpost, the Daily Caller, Vision To America and Free Republic. He also writes an exclusive weekly column for World Net Daily (WND).