In a stunningly unusual turn of events a new Alzheimer’s drug, previously declared a failure back in March, has been resurrected with the pharmaceutical company behind the treatment suggesting the earlier decision to discontinue the research was premature and based on incorrect data analysis.
Earlier this year we covered a blueberry-sized capsule developed by researchers at MIT that would allow diabetics to take their insulin orally rather than by injection. That capsule contained microneedles to deliver the hormone through the stomach lining. Now, the same team has gone a step further, developing a new capsule that would survive a trip through the stomach and deliver its payload to the lining of the small intestine.
Scientists at the University of California, Berkeley have used the CRISPR gene-editing tool to give fruit flies an evolutionary advantage they’ve never had before. By making just three small changes to a single gene, the team gave the flies the ability to effectively eat poison and store it in their bodies, protecting themselves from predators in the process.
An impressive new study is suggesting a simple breath analysis can accurately predict whether lung cancer patients will positively respond to novel immunotherapy treatments. Unlike current methods, which involve studying tissue samples, the new “eNose” device can offer diagnostic advice in less than 60 seconds.
New research from Columbia University, presented at the American Heart Association’s Hypertension 2019 Scientific Sessions, is adding weight to a growing body of evidence connecting high blood pressure to the onset of cognitive decline and dementia. The study suggests treating high blood pressure can potentially slow the rate of cognitive decline.
from The College Fix:
Johns Hopkins professor on child transgender trend: ‘Many will regret this’
Argues that doctors are doing treatment without evidence
The CRISPR tool is fast developing into a powerful way to edit the genes of bacteria, mammals, plants, humans, and even reptiles. It’s often referred to as “genetic scissors,” but a new improvement turns it into a “genetic Swiss Army Knife.” Research led by Caltech has refined the formula to help the tool zoom in on specific organs, tissues or cell types, and give it greater control over what happens next.
Pig hearts may be adapted for human use within three years in a breakthrough move that could clear the UK donor list, a leading surgeon has said.
Sir Terence English, who performed Britain’s first ever successful heart transplant, said his mentee from the 1979 operation will try to replace a human kidney with a pigs before the end of the year.
He believes this could pave the way for more complicated organ transplants in the process called ‘xenotransplantation’.
We’ve seen a number of recent improvements to the CRISPR gene editing method, from enhanced precision to novel techniques to block the process. But despite all these innovations, the technique is generally only able to modify one single gene at a time.