A newly published study has described the successful results in mice of a novel vaccine designed to prevent neurodegeneration associated with Alzheimer’s disease. The researchers suggest this “dementia vaccine” is now ready for human trials, and if successful could become the “breakthrough of the next decade.”
New results have been published from one of the first placebo-controlled clinical trials investigating the effects of microdosing Lysergic Acid Diethylamide (LSD). This Phase 1 trial is the first step in testing whether these kinds of psychedelic microdose methods could be useful as a therapeutic approach for treating Alzheimer’s disease, and while the early data doesn’t identify significant cognitive benefits in microdosing, it certainly demonstrates the method is safe enough to proceed to larger efficacy trials.
Two compelling new studies are building on a hypothesis suggesting age-related dementia is caused by a leaky blood-brain barrier, triggering neuro-inflammation and, ultimately, brain cell damage. The research reveals a novel anti-inflammatory drug can reverse brain aging in senile mice, but experts suggest the studies are interesting but not particularly applicable to human cases of dementia.
As we stare down the barrel of the futuristic-sounding year 2020, it’s a time for reflection on the past decade. The world has seen some pretty major scientific achievements in the last 10 years, as discoveries and developments decades in the making were finally realized. New Atlas rounds up five of the most ground-breaking, history-making milestones of the 2010s.
The notion of wearing lenses over our eyes to correct our vision dates back hundreds of years, with some even crediting Leonardo da Vinci as one of the first proponents of the idea (though that remains somewhat controversial). Material science and our understanding of the human eye have come a long way since, while their purpose has remained largely the same. In the age of wearable computers, however, scientists in the laboratories of DARPA, Google, and universities around the world see contact lenses not just as tools to improve our vision, but as opportunities to augment the human experience. But how? And why?