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New Drug may be Able to Reverse Age-Related Dementia and Stroke

A new discovery into the mechanism behind cerebral small vessel disease may offer new treatments to...
A new discovery into the mechanism behind cerebral small vessel disease may offer new treatments to prevent or even repair damage associated with age-related dementia(Credit:Giovanni_Cancemi/Depositphotos)

Cerebral small vessel disease (SVD) is one of the most commonly associated causes of age-related dementia and stroke. New research, led by the University of Edinburgh, may have finally uncovered the mechanism by which SVD causes brain cell damage, as well as a potential treatment to prevent the damage, and possibly even reverse it. read more

New Drug for RET-Driven Cancers

A new cancer drug, known as BLU-667, has shown promise in human clinical trials
A new cancer drug, known as BLU-667, has shown promise in human clinical trials(Credit: vitanovski/Depositphotos)

A new cancer drug known as cancer drug has moved through phase I human trials, and the results are promising. Taken orally, the drug targets what are known as RET-driven cancers, including types of thyroid and lung cancers, which are normally hard to treat. read more

Spider Silk Helps Cancer Treatment

Immune cells that have absorbed nanoparticles of spider silk (green), carrying peptides for potential cancer vaccines
Immune cells that have absorbed nanoparticles of spider silk (green), carrying peptides for potential cancer vaccines(Credit: Laboratoire Bourquin – UNIGE)

Strong and light, spider silk is one of the most impressive materials in the natural world. Both the real thing and synthetic versions have been used to improve everything from clothing to car seatscooling electronics to preserving produce, making sweet music or helping people hear it, and even patching up severed nerves. Now, scientists in Germany and Switzerland have found a new use for spider silk – wrapping up cancer drugs to protect them until they can reach their tumorous targets. read more

Discriminating Antibiotics

Researchers at Penn State have developed an antibiotic that targets a specific species of bad bacteria,...
Researchers at Penn State have developed an antibiotic that targets a specific species of bad bacteria, without harming the good ones in your gut(Credit: phodopus/Depositphotos)

Antibiotics are effective at killing bacteria (for now, at least), but they aren’t very picky, indiscriminately wiping out both good and bad bacteria. This can upset the fragile balance of your microbiome, which is increasingly being linked to general health and wellbeing. Now, researchers at Penn State have developed a new approach to make a drug that can single out a specific, opportunistic bacteria known as C. difficile. read more

Video Podcast – Trump May Legalize Pot

by: Brent Smith at the Common Constitutionalist

President Donald Trump said Friday that he’s inclined to support a bipartisan effort in Congress to ease the U.S. ban on marijuana, a proposal that would dramatically reshape the nation’s legal landscape for pot users and businesses.

Of course we Constitutionalists, even the common ones, know that it isn’t the federal government’s job to make it illegal or legalize it in the first place. That’s the sole responsibility of the States.

In other words, president Trump would merely be setting right what should have been since the feds started medaling in the State’s business in the first place. read more

New Drug Delivery for Brain Cancer

An artist's rendition of MIT's new nanoparticles, which can carry two forms of drug to combat...
An artist’s rendition of MIT’s new nanoparticles, which can carry two forms of drug to combat brain cancer(Credit: Stephen Morton)

Glioblastoma is one of the most deadly forms of cancer. Affecting the brain, those unlucky enough to receive a diagnosis don’t have many treatment options – and usually a median life expectancy of just over a year. Now, researchers at MIT have developed nanoparticles that could provide hope, crossing the blood-brain barrier and delivering two types of drugs to fight tumors. read more

Tobacco Antibiotics Attacks Superbugs

La Trobe researchers have isolated a peptide from tobacco flowers that could be a promising new...
La Trobe researchers have isolated a peptide from tobacco flowers that could be a promising new antibiotic candidate(Credit: La Trobe University)

The world is in desperate need of new antibiotics, as bacteria continue to evolve and develop resistance to the ones we have. Now, researchers at La Trobe University have found a peptide in the flower of a tobacco plant that could be the first of a brand new kind of antibiotic, hopefully helping us avoid the looming doomsday of superbugs. read more

Oral Insulin Moving to Final Stages of Testing

Insulin in a pill is one step closer to reality as clinical trials progress
Insulin in a pill is one step closer to reality as clinical trials progress(Credit: SergIllin/Depositphotos)

For decades researchers have worked to find a way to orally administer insulin effectively to patients with diabetes. Now this game-changing treatment is one step closer to reality, with pharmaceutical company Oramed embarking on a final Phase 2b human clinical trial to prove the efficacy of its oral insulin before moving to the final stages of trials and registrations that could bring the treatment to market within a few short years. read more

Thinking of Vacationing in Cancún – Think Again

from British website Refinery 29:

The Party Destination That’s Fast Becoming A Murder Capital

Many Brits think of Cancún as an idyllic paradise of white sand, turquoise sea and flatteringly lit beach parties, thanks to its long-held reputation as a popular holiday destination. However the Mexican city is fast becoming known for something else entirely.
Cancún, situated on the coast of the Yucatán peninsula towards the Caribbean Sea, is evolving into a hotbed of murder and violent crime. The murder rate has more than doubled over the past year; more than 100 people have been killed since the start of 2018, with 14 people murdered in a single 36-hour period last month – the highest rate Mexico has ever seen – and five more bodies found in a car just a fortnight later.

The Border Wall Works – Let’s Build It

from Constitution.com:

Trump Gets Amazing Proof of Just How Effective Border Walls Can Be

There is an old saying that good fences make for good neighbors and during his recent trip to California, President Donald trump learned how effective even a makeshift border wall can be.

Trump got some shocking news when he visited the southern border near San Diego, California, on Tuesday, March 13. Not only did he learn that a border wall can be highly effective, but he found out that there doesn’t even have to be some elaborate, high-dollar system to make it effective for stopping illegal border crossings.

Trump headed to the People’s Republic of California this week in part to view some border wall prototypes. read more