A new study from researchers at the Mayo Clinic may shed some light on why certain people can lose more weight than others despite adhering to the same regime of exercise and caloric restriction. Alongside a myriad of other recent medical discoveries, the secret may lie in the unique make-up of our gut bacteria.
by: the Common Constitutionalist
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What would you do to achieve a goal? Many have gone to extraordinary lengths to get where they want to go. But for a dream to become realty, motivation is the key. And not just motivation, but self-motivation.
Most understand that being motivated by others in easier by far. This is the reason many do not achieve their goals. Self-motivation is hard. There is no one standing behind you telling you to push through the pain, get up at the crack of dawn, or work another hour or two. It’s all on you.
But if somebody wants something bad enough, very little can stand in they way of that end. A shining example of this is one William Guinn, Jr. of Abilene, Texas. No – his dream wasn’t to cure cancer or become rich and famous. His dream was simply to join the Army.
Eating a full English for breakfast can help you lose weight, a new study suggests.
Research shows that a meal high in protein instead of carbohydrate or fiber for breakfast can fight off hunger and avoid the urge to over-eat later in the day.
A hearty sitting of foods like sausage, egg or bacon instead of low-fat cereals or fruit for the first meal of the day helps to curb hunger throughout the morning and cut the number of calories eaten at lunch time, experts claim.
Gut microbes may be another way to tackle obesity, new research suggests.
Could a transplant of gut bacteria be the key to tackling obesity?
Scientists found that by altering the levels of gastric bugs in mice, they were able to induce rapid and significant weight loss.
The change occurred after bacteria from obese mice that had undergone gastric bypass surgery were transplanted into ordinary animals.
Surgery had the effect of altering the make-up of the gut flora, introducing a different balance which promoted slimming.
When this new mix of microbes was transferred to non-obese mice, the weight loss benefits were transferred too.
The U.S. research shows that gastric bypasses do more than prevent food being digested. Much of their impact is due to altered ecology in the gut.
‘It may not be that we will have a magic pill that will work for everyone who’s slightly overweight,’ said study leader Dr Peter Turnbaugh, from Harvard University, Boston.
‘But if we can, at a minimum, provide some alternative to gastric bypass surgery that produces similar effects, it would be a major advance.’
Gastric bypasses work by rearranging the gut so that it accommodates less food.
The research showed that after surgery different kinds of microbe began to take over. In particular, the gut became dominated by verrucomicrobia and gammaproteobacteria. In contrast levels of the Firmicutes family of bugs fell.
It took less than a week for the rebalancing to occur, and the effect continued for months afterwards.
The new population of bugs appeared to drive weight loss, and continued to do so when transferred to a non-obese group of mice that had not undergone a gastric bypass.
‘Simply by colonizing mice with the altered microbial community, the mice were able to maintain a lower body fat and lose weight – about 20 per cent as much as they would if they underwent surgery,’ said Dr Turnbaugh.
He suspected an even more dramatic result would have been seen if the mice receiving the bugs had been fattened up beforehand.
How particular populations of microbes induce weight loss remains unclear.
The answer may be linked to waste products the bugs excrete, according to the research published in the journal Science Translational Medicine.
Along with the altered microbes, the scientists found changes in the concentration of certain short-chain fatty acids. Previous studies have suggested the molecules may trigger signals that cause the body to speed up metabolism, or store fewer calories as fat.
‘A major gap in our knowledge is the underlying mechanism linking microbes to weight loss,’ said Dr Turnbaugh. ‘There were certain microbes that we found at higher abundance after surgery, so we think those are good targets for beginning to understand what is taking place.’
Co-author Dr Lee Kaplan, from Massachusetts General Hospital in Boston, said: ‘We need to learn a good deal more about the mechanisms by which a microbial population changed by gastric bypass exert its effects, and then we need to learn if we can produce these effects – either the microbial changes or the associated metabolic changes – without surgery.
‘The ability to achieve even some of these effects without surgery would give us an entirely new way to treat the critical problem of obesity, one that could help patients unable or unwilling to have
Attribution: Anna Hodgekiss, Mail Online