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Artificial Nanoparticles Sniff Out Cancer

Researchers have developed artificial nanoparticles that can help the immune system fight cancer
Researchers have developed artificial nanoparticles that can help the immune system fight cancer

The best way to fight off cancer might be to strengthen the body’s immune system and help it identify and kill tumors. This field of study is known as immunotherapy, and while it’s showing promise it can be quite expensive. Now, researchers at the University of Wisconsin-Madison have developed artificial nanoparticles that should be cheaper and easier to produce.

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Gas Embolotherapy Starves Tumors

Blowing bubbles in the blood could kill cancer with both barrels

Researchers have found that gas embolotherapy (blowing bubbles in the blood) could fight cancer in two...
Researchers have found that gas embolotherapy (blowing bubbles in the blood) could fight cancer in two ways(Credit: delfoto/Depositphotos)

Cancer can be a tricky foe, so the best way to fight it might not be with a direct attack, but to cut off its supply lines. One such method, known as gas embolotherapy, involves creating tiny bubbles in the tumor blood vessels, which block the blood supply and starve the cancer out. Now, researchers from China and France have found that the technique could also deal a second blow as a drug delivery system. read more

New Drug for RET-Driven Cancers

A new cancer drug, known as BLU-667, has shown promise in human clinical trials
A new cancer drug, known as BLU-667, has shown promise in human clinical trials(Credit: vitanovski/Depositphotos)

A new cancer drug known as cancer drug has moved through phase I human trials, and the results are promising. Taken orally, the drug targets what are known as RET-driven cancers, including types of thyroid and lung cancers, which are normally hard to treat. read more

Enzymes Cause Cancer to Die of Old Age

Cancer hijacks a natural anti-aging enzyme to make itself immortal, and now scientists have found a...
Cancer hijacks a natural anti-aging enzyme to make itself immortal, and now scientists have found a way to counteract that process(Credit: Sashkin7/Depositphotos)

At the cellular level, aging and cancer are two sides of the same coin. The mechanism that limits a cell’s lifespan can be slowed down, but that can turn them cancerous, as they divide unchecked.

Now, scientists at EPFL have found a way to manipulate that mechanism to effectively turn off cancer’s immortality, letting it die slowly and naturally. read more

A Cancer Kill Switch

Researchers at Northwestern University have developed a way to trigger an ancient cancer "kill switch" hidden...
Researchers at Northwestern University have developed a way to trigger an ancient cancer “kill switch” hidden in our genes(Credit: ralwel/Depositphotos)

Cancer is one of our most persistent enemies, but while we now have advanced immune systems to fight the good fight, how did early multicellular life manage to stave it off? A genetic “kill switch” seems to have been the original weapon of choice, and now researchers at Northwestern University believe they’ve discovered a way to trigger that mechanism. This knowledge could potentially pave the way to a therapy where cancer cells commit suicide, which would be impossible for cancer cells to adapt a resistance to. read more

STINGel Doesn’t Give Cancer a Chance

A scanning electron microscope image of the injectable cancer-fighting hydrogel, dubbed STINGel
A scanning electron microscope image of the injectable cancer-fighting hydrogel, dubbed STINGel(Credit: Hartgerink Research Group/Rice University)

The cure for cancer might have been inside us all along – our own immune system. The trick is to give it a boost to find and destroy those rogue cells, and that’s the focus of the field of immunotherapy. To that end, a new hydrogel has been developed that can be injected directly to the site of a tumor, where it stays to slowly release its payload of immunotherapy drugs for longer.

Put the two into a ring, and the immune system will win every round against cancer. To give itself a fighting chance, the Big C instead focuses its attention on stealth attacks, using a variety of tactics to evade detection by the immune system until it can grow strong enough to overwhelm the body. read more

Wearable Technology Can Spot Cancer

Wearable technology that can predict cancerous growths ‘several months’ before they form are just around the corner, according to one technology expert.

Nokia’s chief says the firm is working on a scanning device that will pick up on biomarkers that indicate the conditions needed for abnormal cell growth to happen.

A number of other medical innovations have also been envisaged that will make use of ultra-fast 5G mobile internet networks in the future.

That includes remote surgery conducted from across the world, as well as ambulances that are able to transmit data to a hospital ahead of its arrival.

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A Cancer Vaccine Could be Coming

A golden nanostar, seen here under an electron microscope, is a key part of a new ...
A golden nanostar, seen here under an electron microscope, is a key part of a new treatment that might eventually lead to a cancer vaccine (Credit: Duke University)

In experiments on mice, researchers at Duke University have found that combining two different techniques for fighting cancer is more effective than either treatment is on its own. In one case, the mouse’s immune system not only destroyed the tumor, but stayed strong enough to ward off a later injection of cancer cells, raising hopes that the strategy could one day lead to a viable cancer vaccine.

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Magnets can Spot Cancer

Tiny magnetic beads coated in sugar could help doctors to check if a cancer has spread. Once injected into the patient, the beads can be detected using a handheld magnetic wand — similar to a metal detector — and are used to identify the lymph nodes nearest to the cancer.

The lymph nodes form part of the lymphatic system, which drains fluid from tissues all over the body back into the bloodstream. If cancerous cells get into this system, the disease can then spread to other parts of the body.

The key to determining if cancer has spread is identifying the sentinel node — the lymph node that is nearest the tumour.

Tiny magnetic beads coated in sugar could help doctors to check if a cancer has spread
Tiny magnetic beads coated in sugar could help doctors to check if a cancer has spread

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Cancer Drug Kills Every Kind of Tumor

 

Stanford University scientists have discovered a single drug that has killed or shrunk every kind of cancer tumor it has been used against — a new anti-cancer weapon that some have described as a kind of medical Holy Grail.
 
The drug blocks a protein produced in large amounts by cancer cells — called CD47 — that keeps the body’s immune system from fighting tumors. By shutting down the CD47 production, the new antibody drug effectively leaves cancer cells vulnerable to the body’s own natural defense mechanisms.

Tests of the drug found that it destroyed several kinds of human cancer cells transplanted into mice — including breast, ovary, colon, bladder, brain, liver, and prostate tumors — by prompting the rodents’ immune systems to kill the cancer cells.Continue Reading